Pathophysiology of sepsis-triggered takotsubo syndrome

Non-triggered Takotsubo-syndrome in metabolic myopathy.

Takotsubo-syndrome (TTS) is characterized by sudden onset chest-pain and dyspnea, electrocardiographic changes resembling acute coronary syndrome, minimal elevation of cardiac enzyme levels and transient wall-motion abnormalities in the absence of coronary artery obstruction [1]. Although TTS occurs frequently after emotional or physical stress, non-triggered TTS, is reported in 10–66% of the c...

Seizure-triggered Takotsubo syndrome rarely causes SUDEP

Since almost 20 y it is known that seizures may trigger Takotsubo syndrome (TTS). Since then it has been repeatedly proposed that TTS could be the cause of sudden unexpected death in epilepsy (SUDEP). A review of the so far reported cases of seizure-triggered TTS was carried out to see how often seizure-triggered TTS is fatal. Altogether 59 papers were identified which reported altogether 74 pa...

“dobutamine stress testing”-triggered mid-ventricular takotsubo syndrome

Broken Heart Syndrome (Takotsubo Cardiomyopathy) Triggered by Orthotopic Liver Transplantation

Upon extensive review of literature, Takotsubo cardiomyopathy post orthotopic liver transplant has been reported in only few cases. Herein we present a case of Takotsubo cardiomyopathy post orthotopic liver transplantation. In our case, we aim to illustrate the importance of early recognition of this condition since stress induced cardiomyopathy is an underestimated cause of cardiac complicatio...

More about seizure-triggered Takotsubo syndrome and SUDEP

More about seizure-triggered Takotsubo syndrome and SUDEP Response to the Letter by Madias et al. We appreciated to read the Letter to the Editor by Prof. Madias concerning ''Seizure-triggered Takotsubo syndrome rarely seems to cause SUDEP'' [1]. We do not agree with the statement that seizures after subarachnoid bleeding (SAB) are the most common central nervous system (CNS) trigger of TTS [2]...